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In an article published in the journal JAMA Ophthalmology in May 2024, a group of researchers concluded that their observational study demonstrated an association between NAION and use of semaglutide, the active ingredient in Ozempic and Wegovy

During fasting periods, tirzepatide continues suppressing ghrelin (the hunger hormone) and enhancing satiety signals, which actually aligns well with fasting goals because the medication makes extended fasts more tolerable by reducing cravings