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The treatment effect was then evaluated using Cox proportional hazard regression, with cage assignment included as a random effect and batch as a covariate, using statistical software R (version 3.4.1) with package coxme

In some embodiments, the pharmaceutical formulations or compositions described herein are stable with respect to pH over a period of any of at least about 1 day, at least about 2 days, at least about 3 days, at least about 4 days, at least about 5 days, at least about 6 days, at least about 1 week, at least about 2 weeks, at least about 3 weeks, at least about 4 weeks, at least about 5 weeks, at least about 6 weeks, at least about 7 weeks, at least about 8 weeks, at least about 1 month, at least about 2 months, at least about 3 months, at least about 4 months, at least about 5 months, or at least about 6 months

This oxygen species may penetrate cellular membranes and react with nuclear DNA [7]

This interplay between genetic predisposition and medication quality should be interpreted with a qualified healthcare provider

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