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Studies have confirmed measurable plasma L-dopa levels post-fava bean ingestion, suggesting clinical activity (Rabey et al

In recent years, the global prevalence of NDDs has steadily increased, with an alarming trend toward earlier onset in younger populations

Preclinical pharmacokinetic-pharmacodynamic data has shown that beneficial effects of ARA 290 occur when plasma concentrations exceed 1 nmol/L (2)

Treatments with the NOS inhibitor L-NAME and iNOS inhibitor GW274150 are proven to improve inflammation response, and a trend toward a reduction in synovial thickness is observed (154, 155)

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The role of nerve growth factor in a model of visceral inflammation