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For example, SS-31 given to rodents during resuscitation from hemorrhagic shock improved survival and reduced lung injury by lowering mitochondrial ROS in immune cells (107)

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In cell and mice studies, butyrate also affects gene expression and cell signaling in ways that could reduce development of colorectal cancer

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Activation of caspase-1 by inflammasomes induces pyroptosis, an inflammatory form of programmed cell death (Wroska et al., 2024)