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As evidenced in the SURPASS trials, this novel GIP/GLP-1 dual-acting hormone therapy is yielding significant improvements in A1c and weight loss

Individual results may differ based on the length of treatment

Additionally, immunomodulatory agents like tofacitinib, a JAK inhibitor, carry risks of increased susceptibility to infections, particularly in immunocompromised individuals, as well as potential cardiovascular and thromboembolic events [153]

Results The model detected 112,274 T2D patients who did not receive insulin therapy and started GLP1-receptor agonists (28,081 individuals) or SGLT2 inhibitors (84,193 individuals) in the United Kingdom (UK) from January 2013 to October 2020

It launched under the brand name Mounjaro for diabetes management in 2022 and Zepbound for weight loss in 2023

The wellbutrin and tirzepatide guide covers one common combination