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developed GSH-triggered self-immolative nitric oxide prodrug and functionalized it onto various materials such as albumin, 4-arm-PEG, and silica nanoparticles to improve lymphatic drainage and cancer cell uptake (Fig

1 Mechanistically, treatment raised the Bcl-2/Bax ratio and reduced apoptosis markers (cleaved caspase-3 and PARP) in the dermal papilla cells, elevated VEGF production, and decreased TGF-1 secretion from dermal fibroblasts

Zheng and Zhang, 2023)

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17 Early findings support that restoring Glutathione balance may improve cognitive performance and reduce oxidative stress in the aging brain, thanks to its powerful antioxidant properties, though findings remain preliminary