Maintaining optimal levels of folate and Vitamin B12 is crucial for various bodily functions, including the production of red blood cells, DNA synthesis, and proper neurological function
In contrast, when a healthcare provider diagnoses B12 deficiencyvia blood tests and clinical evaluationB12 injections serve a medical purpose: correcting a documented biochemical imbalance and preventing the progression of serious conditions
This efficient excretion helps keep the risk of a vitamin B12 overdose relatively low, despite its storability (Havard, 2023)
After incubation of fibroblasts with 500 microM of OHCbl, a 75% decrease of intracellular cyanide was observed, with concomittant formation of intracellular cyanocobalamin CNCbl (intracellular/extracellular ratio: 158)
High doses of vitamin B12 may be harmful in people with certain types of liver disease, such as liver failure
However, your metabolism will be even higher if you have a significant amount of muscle mass