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GLP-1s are injectables, and you have to keep taking them

Considering the short half-life of small molecule oral GLP-1 receptor agonists, perhaps approaches to increase the duration of small molecules with a modified-release formulation may lead to improvements in long-term cardiovascular benefits

Supplementary material The Supplementary Material for this article can be found online at: References 1 World Health Organization

J Investig Dermatol 126:10361042

Understanding the role of the cytoprotective transcription factor nuclear factor erythroid 2-related factor 2lessons from evolution, the animal kingdom and rare progeroid syndromes

Thyroid cancer risk Early animal studies on rodents found that Ozempic could cause medullary thyroid cancer, though this has not been shown in people