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When the brain perceives stress, it signals the adrenal glands to release cortisol, the body's primary stress hormone

Cell proliferation and clonogenic assays The TACS XTT cell proliferation assay kit (Trevigen) was used for cell proliferation assays as described previously

TFEB functions as a master activator of the autophagy-lysosomal pathway by binding to coordinated lysosomal expression and regulation (CLEAR) motifs and promoting the expression of genes involved in autophagosome formation, lysosomal function, and fusion events

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Drawing from the STEP clinical trials, which showed significant weight reduction over 68 weeks, we understand that consistency is the key to longevity

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