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Procedures: Using a sandwich culture technique, canine primary hepatocytes were exposed to serial dilutions of ITZ

Mass spec confirmed the correct sequence without ambiguity

We also demonstrated that cARLA treatment improved the predictive value of a human stem cell derived co-culture BBB model not only for small molecule drugs but also for targeted nanoparticles [40]

GLP-1 receptor agonists are a class of medications that mimic the glucagon-like peptide-1 hormone, enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptying to lower blood glucose levels

JCI Insight 7 , e159863 (2022)