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People who were taking them tended to lose a little bit of weight and so the drug companies that manufactured them wondered if people taking larger doses would lose more weight (at least short term.) They did, and then applied for and received FDA approval here in the US specifically for weight loss

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Partial least squares-discrimination analysis (PLS-DA) and the heatmap showed a clear classification of the metabolomes between four groups ( Figures 2A, B )

ClinicalTrials.gov A Study of Retatrutide (LY3437943) Once Weekly in Adults With Obesity and Knee Osteoarthritis (TRIUMPH-4)

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It is a tripeptidea small protein moleculemade up of three specific amino acids: cysteine, glycine, and glutamic acid