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When you wake up the next morning, you are at peak dehydration leading to headaches and an overall uncomfortable feeling

It also helps your body make DNA, the genetic material in all your cells

This makes me suspicious of the quality of colagen in the structure of the tendon

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Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation

This matters most for people whose bodies struggle to absorb B12 from food or pills