A common investigational regimen employs 0.5 g kg1 of combined amino acids (maximum 40 g total), infused over 30 - 45 minutes with equal parts arginine and citrulline
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If the liver is exposed to an excess of APAP, however, these detoxification processes are overwhelmed, and APAP is instead metabolized by the cytochrome P450 enzyme CYP2E1 into the highly reactive and toxic metabolite NAPQI 4
The product does not contain preservatives or genetically modified ingredients
It contains four amino-acid residues and is therefore a tetrapeptide
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