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Cytoprotective Pathways: FAK-Paxillin Signaling and Growth Hormone Receptor Interaction Focal Adhesion Kinase: The Structural Survival Signal Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that integrates signals from integrins the transmembrane proteins that anchor cells to extracellular matrix with intracellular survival and migration pathways

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Consistent with obesity-induced oxidative stress, oxidative DNA damage (as shown by 8-OH-dG staining) and DNA segment (as shown by TUNEL staining) in the atira was aggravated after HFD, and were alleviated by LCA (Figures 4NQ)

Pour rappel, ce phnomne est connu pour tre lorigine de nombreux dgts cellulaires et tre impliqu dans le vieillissement prmatur des cellules