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Tafuri, A, DeFelice L, Goodacre A, Fenu S, Petrucci M, Mascolo M, Alimena G, Petti M, Meloni G, Mandelli F, Andreeff M

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Patients with type 2 diabetes who have established diabetic retinopathy at treatment initiation face the highest risk, particularly when experiencing rapid A1c reductions within the first 16 weeks of therapy

These pathways affect collagen remodeling, tissue regeneration, and other cellular signals involved in healing