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CagA modulates host cell iron homeostasis and fundamental metabolic functions of the bacterial cell, promoting the synthesis of polyunsaturated ether phospholipids (PUFA-ePLs) through increased expression of alkylglycerone phosphate synthase and 1-acylglycerol-3-phosphate O-acyltransferase 3, resulting in susceptibility to ferroptosis in GC cells [49]

Some patients also worry that recurring symptoms reflect ongoing exposure or reinfection

Nucleic Acids Res 53:D609D617 Das M, Sreedharan S, Shee S, Malhotra N, Nandy M, Banerjee U, Kohli S, Rajmani RS, Chandra N, Seshasayee ASN et al (2023) Cysteine desulfurase (IscS)-mediated fine-tuning of bioenergetics and SUF expression prevents Mycobacterium tuberculosis hypervirulence

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Epub 2012 Feb 28

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