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These are small pharmacology details on paper

Toxicol Rep 5:10981106

Serious side effects from Orlistat are rare but can include liver problems, while Wegovy has been linked to serious side effects such as pancreatitis and thyroid cancer risk (specifically medullary thyroid carcinoma)

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What are the main challenges companies face when trying to improve efficacy or safety in this competitive class

Regulatory pathways for biomarker approval should be clarified to facilitate clinical implementation of validated markers (May et al., 2010)