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Their composition and use are entirely unregulated, adding to the hazards they pose

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The number of studies available in humans was limited, and the results were mixed

The oral delivery filings are the most interesting forward-looking signal in Lilly's estate: Lilly has already demonstrated with oral semaglutide (via the Novo-Lilly prior-art relationship) and orforglipron (its own oral small-molecule GLP-1) that the company takes the oral incretin vector seriously

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