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Worsening of diabetic retinopathy has been observed primarily with semaglutide during rapid glycemic improvement, particularly in patients with pre-existing retinopathy

The body interprets this as a stressor, and the HPG axis temporarily dials back LH production

It is a type of medication that also helps patients with type 2 diabetes

Patients describe feeling satisfied with smaller portions, experiencing reduced cravings for high calorie foods, and finding it easier to make healthier food choices

C-reactive protein and inflammatory markers CRP, the most commonly measured marker of systemic inflammation, begins declining within the first three months of semaglutide treatment

Semaglutide is used as a GLP-1-only comparator