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Many patients experience gastrointestinal side effects during treatment, particularly in the initial weeks, and caffeine can sometimes exacerbate certain symptoms

Jurado-Priego LN, Cueto-Urea C, Ramrez-Expsito MJ, Martnez-Martos JM

That said, the National Center for Complementary and Integrative Health (a division of the National Institutes of Health) recently weighed in on the popularity of berberine

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Clinical Trials: The Primary Access Route Enrolling in a TRIUMPH trial is the only way to receive pharmaceutical-grade retatrutide under medical supervision