glp 1 oral drops side effects Your guide to GLP-1 Ozempic and GLP-1 Drugs: Risk

Joshua Silva, MD Nov 7, 2025 13 min read Updated: Apr 17 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As GLP-1 and GLP-1/GIP medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) continue to transform medical weight management, one question comes up repeatedly: Do these medications cause muscle lossor even muscle wasting

In the Phase 2 NEJM trial (2023), participants on 12 mg lost an average of 24.2% of body weight at 48 weeks

Take with a full glass of water

Side Effects Administration The biggest difference between GLP-1 shots and pills is your routine for taking the medication

GLP-1 medications are FDA-approved for the treatment of type 2 diabetes and, at higher doses, for chronic weight management in people with obesity

Tufts Now: Why is it important for people taking GLP-1s to incorporate nutrition and lifestyle interventions into their routine, and what happens if they dont