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Andersen, P

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Ignoring Hydration Many side effects improve dramatically when hydration improves

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Cardiovascular and Metabolic Benefits Although not yet conclusively proven, early data suggest that Tirzepatide may: Improve blood pressure and lipid profiles Reduce markers of inflammation and insulin resistance Potentially lower cardiovascular risk, though large outcome trials like SURPASS-CVOT are underway to confirm this Such benefits are particularly relevant, as cardiovascular disease is the leading cause of death among people with type 2 diabetes

But if they occur soon after starting a GLP-1 RA especially alongside vomiting, diarrhea, or poor oral intake electrolyte imbalance should be on the list of possibilities