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13 Their use should be guided by assessment of absolute risks and benefits of treatment for individual patients, taking into consideration the time required for benefit (known as "time to benefit"), patient preferences, and estimated life expectancy

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doi: 10.1016/j.clnesp.2020.03.008

If you take your dose early once, avoid falling into a pattern of early injections every week, as this gradually compresses your dosing schedule and could eventually lead to unintended dose frequency changes

Metabolism 120 , 154798 (2021)

This makes it useful beyond specific injury applications patients with chronic inflammation, autoimmune conditions, or post-intensive-exercise inflammation report meaningful reductions in systemic inflammatory markers