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On the right, the cellular driver is revealed: an imbalance of immune cells, where a predominance of 'M2' macrophages triggers "woody" fibrotic tissue changes that obstruct natural fluid drainage and drive abnormal, disproportionate fat expansion

An informed patient is a safer patient

GLP-1 receptor agonist users had a significantly lower risk of all-cause mortality at both one year (hazard ratio [HR] 0.29) and two years (HR 0.36)

Int J Mol Sci 23(9):4809

Given the chronic, fluctuating course of both BD and MetS, TPE delivered through a sustained, multidisciplinary framework, incorporating psychiatry, nutrition, behavioral therapy, and primary care, enables patients to become active, informed partners in their health