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Leidy in The American Journal of Clinical Nutrition found that higher-protein diets during weight loss improve satiety and help preserve fat-free mass

The use of second-line ADMs was commonly accompanied by insulin or metformin in 80-90% of cases

Some individuals with higher starting weights respond excellently to moderate doses

They do so by stimulating the release of insulin, slowing down the emptying of the stomach, and reducing the production of glucose by the liver

Emerging evidence also suggests GLP-1s increase cerebral blood flow through arteriolar vasodilation and may promote angiogenesis, helping restore metabolic support in vulnerable brain regions [13]

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