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Nat Genet 2014

DOX-induced cardiotoxicity involves oxidative stress, mitochondrial dysfunction, and alterations in NOS and ROS pathways

This integration compromises membrane function, reducing biological membrane fluidity and leading to impaired cellular energy production, disruption of biological membrane integrity, and restricted material exchange, collectively disrupting normal cellular physiology

Blancquaert L, Baguet A, Bex T, Volkaert A, Everaert I, Delanghe J, Petrovic M, Vervaet C, De Henauw S, Constantin-Teodosiu D, Greenhaff P, Derave W

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Poulard, C., Noureddine, L