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Crowell MD, Cheskin LJ, Musial F

To maximise the long-term effects, it's important to maintain a healthy lifestyle through diet and exercise

Safety: Clinically tested oral supplements are safer for long-term use

[11] [12] Management strategies for common gastrointestinal side effects include gradual dose titration following FDA-approved schedules, eating smaller and more frequent meals, avoiding high-fat foods, staying well-hydrated, and temporarily reducing the dose if symptoms become intolerable

Thus, 10 days of dosing in a parallel-group design as done in the two current trials was assessed to be the best possible compromise considering both clinical feasibility and regulatory guideline recommendations

Label all prepared research materials clearly and adhere to institutional stability controls and disposal protocols for unused or contaminated materials