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In December 2014, it was deemed a suitable option for chronic weight management in addition to a calorie reduced diet and physical activity

Enhancing Metabolic Health and Blood Sugar Control Some research suggests that a diverse and healthy gut microbiome can positively influence insulin sensitivity and help regulate blood sugar levels

Tirzepatide is appropriate for medically-supervised weight loss in adults with BMI 30 or 27 with obesity-related comorbidities

J Alzheimers Dis 2013

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Patients with a history of anorexia nervosa or bulimia nervosa require particularly careful evaluation, as rapid weight loss may not be appropriate