It blocks adenosine A1 and A2A receptors, reducing fatigue and increasing wakefulness., However, studies show that it does so with slightly greater potency and fewer reports of overstimulation., Recent trials have demonstrated paraxanthines ability to improve executive function, decision-making, short-term memory and vigilance under both mental and physical fatigue. In one study, participants who consumed paraxanthine exhibited greater improvements in psychomotor vigilance and fewer decision-making errors compared to caffeine users, both before and after running. Paraxanthine mirrors caffeines impact on energy metabolism by increasing plasma epinephrine and free fatty acids, mechanisms linked to improved endurance and motivation.,, Importantly, it does so without elevating theobromine or theophylline levels, which are associated with many of caffeines less desirable effects
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Biological properties and antimicrobial potential of cocoa and its effects on systemic and oral health
an ad libitum test meal was used to measure energy intake during intravenous infusions of either PYY3-36 or OXM or combined PYY3-36/OXM
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Eur J Drug Metab Pharmacokinet (2006) 31(2):10916
