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After repeated administration, rats in the short-access paradigm exhibited lower daily and cumulative METH intake than saline controls, with this effect becoming apparent on the second day of treatment and continuing throughout the study, while LIR did not affect METH-taking behavior in the extended-access paradigm

This disparity correlated with a more robust tumor-specific T cell response and intratumoral accumulation of CD8+ T cells in JAX mice

Isenovic (2015) Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases, Critical Reviews in Clinical Laboratory Sciences , 52:2, 70-85, Baldelli, S., Ciccarone, F., Limongi, D., Checconi, P., Palamara, A

V.PendletonN.HoranM.PaytonA.WorthingtonJ.et al (2008)

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Initial effects include increased energy and improved mental clarity within the first week