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Primary Intended Use: In vitro and in vivo laboratory research only

Nambiar S, Osei E, Fleck A, Darko J, Mutsaers AJ, Wettig S

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Serotonin syndrome symptoms may include mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)

Since TMABADH.1S could be expressed well and showed about 0.9 U mg 1 activity, it was selected for further work on the carnitine biosynthetic pathway