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Unlike prior reviews that focus on individual herbs or broadly defined adaptogens, the present review integrates mechanistic, preclinical, and clinical evidence across these three agents to highlight their complementary rather than redundant actions

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Another study showed that elevated insulin levels promote the proliferation of thecal cells and increase the secretion of androgens, including luteinizing hormone (LH), while also upregulating the expression of cytochrome P450 and insulin growth factor-1 (IGF-1) receptors (107)