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CSP analysis was used to observe the interaction sites based on changes in the surrounding chemical environment

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Scientific References (External Links) Nature Chemical Biology: Small molecule inhibitors of nicotinamide N-methyltransferase View Study Biochemical Pharmacology: Nicotinamide N-methyltransferase: A promising target for treating metabolic disorders View Study FASEB Journal: Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity in mice View Study Journal of Biological Chemistry: Inhibition of nicotinamide N-methyltransferase in vivo regulates cellular energy metabolism View Study

However, BAT from Ssu72 aKO mice appeared paler and exhibited enlarged adipocytes with increased lipid droplet accumulation compared with WT mice under both NCD and HFD conditions (Supplementary Fig