what exactly does glp 1 do The promise and peril of GLP-1 agonists: we (and don't) know as of August 2024 What is GLP-1? The Hormone

Ozempic and other GLP-1 medications directly mimic the GLP-1 hormone at much higher levels to control appetite and slow digestion

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Beyond weight management and metabolic health, research is exploring whether GLP1s may reduce the risk of dementia, for example, which is increasingly linked to insulin resistance in the brain

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The semaglutide and tirzepatide trials changed that expectation: Semaglutide 2.4 mg once weekly produced average weight loss around 15% at ~68 weeks in adults without diabetes, with a substantial fraction of participants losing 1520% of baseline weight