From this concept, the entire development program was born
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Stability of peptides in solution: A review of degradation pathways
Studies using rat models with transected Achilles tendons showed BPC-157 treatment resulted in accelerated recovery with increased load to failure, superior Achilles Functional Index scores, enhanced mononuclear cell infiltration, improved collagen fiber organization, and smaller persistent defects compared to untreated controls
Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B
In COPD studies, GHK-Cu at 10 nanomolar concentration restored lung fibroblasts ability to contract and restructure collagen, a function that is severely compromised in COPD patients