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In relation to CaMKK2, a pharmacogenomic study using a methamphetamine-induced model of bipolar disorder in mice found that valproate treatment increased Camkk2 mRNA expression in the brain caudate nucleus [155]

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Finally, two ketothiolase (with a CoA-acyltransferase) generate acetyl CoA and a new acyl-CoA two atoms shorter, which continues through the cycle as far as octanoate, which can then be subjected to mitochondrial -oxidation

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