148 These drugs act by simultaneously targeting three different agonists GLP-1R, the GIPR, and the GCGR
experimental studies with other GLP-1 analogues (exendin-4 and liraglutide) have shown evidence of inhibition of oxidative stress, decreased apoptosis and prevalence of injured cells, decreased vascular proliferation, and increased c AMP levels in neurons and anti-inflammatory activity in microglial cells [67]
The absolute risk for these complications however is extremely uncommon, less than 1 per cent per year of use (Eckert)
GLP mimetics are currently widely used in the treatment of Type 2 diabetes while both physiological and pathophysiological effects on the exocrine pancreas are less clear
D., Pedersen, J., Knop, F
Beneficial effects of GLP-1 agonist in a male with compulsive food-related behavior associated with autism