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47,53,56 GSIS is a biphasic event in healthy humans: first phase insulin release lasts only a few minutes whilst the prolonged second phase sustains insulin secretion to deal with post-prandial nutrient loads

doi: 10.1056/NEJMoa2401943 204 SkovJDejgaardAFrkirJHolstJJJonassenTRittigSet al

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Recently, for example, European regulators linked Ozempic to a risk of non-arteritic anterior ischemic optic neuropathy, a condition potentially causing blindness in some patients with type 2 diabetes