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The oxygen-rich functional groups on GO facilitate pH-responsive drug release, with studies showing 97% doxorubicin release at tumor-like acidic pH (5.0) versus 33.5% at physiological pH (7.4) [89]

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Case Presentation A 71-year-old female with no prior psychiatric history presented with sudden onset of: Severe anxiety Insomnia Cognitive dysfunction Fatigue Severe neck and shoulder pain Abdominal pain New intolerance to previously well-tolerated foods Symptoms began within months of moving into a new office building , suggesting a potential environmental trigger