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When the elimination half-life is minutes, peptide is being cleared roughly as fast as it is absorbed, and the peak plasma concentration achievable is far below what a bolus IV injection produces

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They elucidated their biology and physiological function and played critical roles in the design and testing of therapies informed by their initial and subsequent discoveries These three scientists are awarded for a combined body of work with significant impact on the field of diabetes and short bowel syndrome but are also recognized for their individual discoveries that underpin the translational results