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Durian ( Durio zibethinus L.), a crucial tropical fruit crop, holds significant economic value in Southeast Asia

The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide

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Additionally, the elderly may need careful dosage adjustment due to potential sensitivity to the drug