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While CB-839 inhibited the proliferation of patient-derived glioma cell lines, it did not affect cell viability (103).In NSCLC, KEAP1 mutant NSCLC cell lines exhibit a dependence on Gln, and the GLS inhibitor CB-839 can inhibit Gln metabolism to exert anti-tumor effects (104)
2018 Feb;25(4):3765-3774
European Journal of Clinical Pharmacology
Liposomal: Cng ngh liposome gip tng cng kh nng hp th glutathione vo c th, gip sn phm pht huy hiu qu tt hn
as a result, renal ammonia production contributes to systemic hyperammonemia [49]
Administer the standard dose as soon as you remember, then resume your regular weekly schedule
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