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Biomedicines 8 , 284 (2020)

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Th17 cells are mostly responsible for IL-17 production, but new research shows that innate immune cells, such as T cells, neutrophils, and mast cells, also play a role in IL-17 release in psoriasis (Isailovic et al

Preclinical safety evaluations revealed no toxicity in acute studies with SD rats and beagles following intravenous/intramuscular administration [10]

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5.2 Induction of NO synthesis in endothelial cells Endothelial-type nitric oxide synthase (eNOS) has been reported to have cardioprotective functions (Helmstdter et al., 2020)