They analyzed data from over a million patients, all of whom were grappling with opioid use disorder (OUD) or alcohol use disorder (AUD), to see what impact GLP-1 medications might have
Pyridinoline (PYD) collagen crosslinks are formed during the extracellular maturation of fibrillar collagens and released into the bloodstream as mature collagens degrade and are considered bone resorption markers (Kuo & Chen 2017)
Continuing Semaglutide can also help prevent the yo-yo effecta cycle of losing weight, regaining it, and losing it again
10.3390/cancers12071849 14 BuckE.GokhaleP
A 2023 analysis found that participants who discontinued semaglutide after 68 weeks of treatment regained approximately two-thirds of their lost weight within one year
Even though addictions and compulsions differ, both appear to be governed by overlapping reward pathways in the brain, and semaglutide may impact them both in a similar way