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It is estimated that CagriSema could hit the market by late 2025 or early 2026, pending the outcome of Novo Nordisk s phase 3 trials, expected later this year and in early 2025

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However, there are no human trials linking vascular changes to pregnancy results

Moreover, replacements of Lys105 resulted in a reciprocal increase of the K m app (GSSCys) values and decrease of the K m app (GSH) values (Fig

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