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Unknown long-term effects: Generally speaking, most people seem to tolerate short-term use well, however, no one really knows the effects of using higher doses for the long-term

7 8 Both drugs have known limitations and side-effect profiles, and neither cures the condition benefits generally require continued use

"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study

Knowing what changes to look for and when to expect them helps you stay the course during the early weeks when results may not be obvious

It also does not mean stronger is always better

Flare-ups commonly coincide with menstruation, pregnancy, or changes in birth control