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The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]

A BMI of 27 or higher is the lowest threshold, and it only qualifies under Tier 3 alongside specific cardiovascular or metabolic conditions

Lau, David C W

Limitations Article heterogenicity There are several limitations of this review, most of which are due to the nature of the articles included