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Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves orbitopathy

An updated analysis of DMFS reported a 36-month DMFS rate of 84.4% in the pembrolizumab group and 74.7% in the placebo group

Ulmer AJ, Mattern T, Feller AC, Heymann E, Flad HD

Still, they may include restoring blood flow through surgical procedures, managing any underlying conditions contributing to the ischemia, and providing supportive care