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Xu Q, Park Y, Huang X, Hollenbeck A, Blair A, Schatzkin A, et al

53 Additionally, its effects on vascular tone and platelet function may increase bleeding risk, warranting caution in patients with bleeding disorders or those on blood thinners

L cell secretagogues Stimulation of GLP-1 secretion from enteroendocrine L cells is another approach that may be able to realise the therapeutic potential of GLP-1, perhaps in combination with DPP-4 inhibition to prevent the inactivation of the GLP-1 released

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(Victoxa, Saxenda)

Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial