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Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy

Agents that stimulate the adrenergic receptors, such as isoproterenol or salbutamol, activate cell metabolism, reducing the amount of triglycerides stored in the adipocytes

It typically peaks at 24 to 48 hours and resolves over 3 to 7 days

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[10] The first amylin analogue to reach the clinic, pramlintide, demonstrated that the pathway could be drugged, but native-style amylin analogues are short-acting and were used as multiple-daily injections, which limited their appeal for weight management